The Life-Changing Magic of Mushrooms

A single dose of magic mushrooms can make people with severe anxiety and depression better for months, according to a landmark pair of new studies.

Peter Dejong / AP

The doom hung like an anvil over her head. In 2012, a few years after Carol Vincent was diagnosed with non-Hodgkin lymphoma, she was waiting to see whether her cancer would progress enough to require chemotherapy or radiation. The disease had already done a number on her, inflating lymph nodes on her chin, collar bones, and groin. She battled her symptoms while running her own marketing business. To top it all off, she was going through menopause.

“Life is just pointless stress, and then you die,” she thought. “All I’m doing is sitting here waiting for all this shit to happen.”

When one day at an intersection she mulled whether it would be so bad to get hit by a car, she realized her mental health was almost as depleted as her physical state.

That’s when her 27-year-old son sent her a link to an invitation from the Johns Hopkins University School of Medicine, seeking cancer patients to sign up to take psilocybin, the active ingredient in magic mushrooms, to alleviate their anxiety and depression. “Start thinking about all the existential questions you want to ponder while your window is open to the universe!” her son wrote.